Automated chemical synthesis. Part 3: Temperature control systems

Automated chemical synthesis. Part 3: Temperature control systems

Research efforts have been directed towards constructing a fully automated microcomputer-controlled bench-scale 'batch-type' chemical reactor [1-6]. This fully automated reactor can execute repetitive experiments on an approximately 50 ml scale, providing important chemical reaction data during early stages of process development research programmes. The precision and accuracy of the reagent/so...

Automated chemical synthesis. Part 2: Interfacing strategies

Research focused largely on developing new, highly automated tools for the process development laboratory is carried out in the authors' laboratory. The ability to evaluate, characterize and optimize synthetic routes, both quickly and comprehensively, is especially important in the pharmaceutical process development laboratory, where typically in a complex synthetic sequence many reaction param...

Homeostasis part 3: temperature regulation.

Automated chemical synthesis. Part 4: Batch-type reactor automation and real-time software design

The ability to efficiently and comprehensively evaluate synthetic routes at their earliest stage of development is especially important in pharmaceutical process research and development and chemical engineering laboratories [1 and 2]. The evaluation and optimization of typically complex synthetic sequences (involving many reaction parameters) frequently entails bench-scale experimentation of a...

PART 3 Nonlinear Systems